Contamination of the environment by heavy metals is one of the major threats to water and soil as well as human health and phytoremediation has been used to remediate metal-contaminated sites. This study evaluated the remediation potential of Panicum virgatum, Ocimun basilicum and Luffa cylindrica growing on lead irrigated soil. The experiment consists of five levels of lead (0, 200, 400, 600 and 800 mg/L) and the three plants species laid out in Randomized Complete Design with four replicate. Plant root, stem, leaf and the soil samples were analyzed for lead content. Bioconcentration Factor (BCF), Biological Accumulation Coefficient (BAC) and Biological Transfer Coefficient (BCF) were calculated. The results obtained revealed that O. bacilicum and L. cylindrica had BTC, BAC and BC > I but P. virgatum had BTC < 1 which means that O. basilicum and L. cylindrica have the ability to accumulate and translocate lead in their tissues and P. virgatum had limited ability to translocate the metal. The results revealed that lead content in plant tissues is differ significantly (p<0.05) with concentration, species and plant parts. Turkey simultaneous test showed that L. cylindrica was significantly different with O. basilicum and P. virgatum (p<0.05), and O. bacilicum was significantly different with P. virgatum (p<0.05). The lead content in leave is significantly different as compared with stem and root including growing media (p<0.05). Root length is also significantly different with soil and stem. The study recommends the use of all plants in phytoremediation of lead contaminated soil and considered L. cylindrica and O. basilicum as hyperaccumulators.